Release Time:2019-03-10  Hits:

Indexed by: Journal Article

Date of Publication: 2007-08-10

Journal: 中国医药工业杂志

Included Journals: CSCD、ISTIC、PKU

Volume: 38

Issue: 8

Page Number: 561-563

ISSN: 1001-8255

Key Words: 冠心膏贴片;丙烯酸酯压敏胶;丹参酮ⅡA

Abstract: 以丙烯酸酯压敏胶为基质制备冠心膏贴片.通过测定贴片的180°剥离强度和持黏力优化贴片组方,并测定了贴片中丹参酮ⅡA含量以及贴片的体外释放行为.结果表明,贴片的优化组方为:水0.24～0.30g,乙醇0.18～0.24g,丙烯酸树脂0.15g.按优化组方制得的贴片12h体外释放度24.6%,高于市售冠心膏贴剂.