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Comparative studies based on a 3-D graphical representation of protein sequences

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Indexed by:会议论文

Date of Publication:2015-08-20

Included Journals:EI、Scopus

Volume:9226

Page Number:436-444

Abstract:We perform comparisons among protein sequences based on a 3-D graphic representation of proteins [Bai and Wang, J. Biomol. Struc. Dyn., 23, 537 C545 (2006)]. In detail, we make analysis of similarities among nine ATP6 (ATP synthase F0 subunit 6) proteins by comparing their corresponding 3-D curves and select the geometric center and the correlation matrix from the 3-D curve, as well as a angle metric for the construction of the phylogenetic tree. In comparison with the traditional alignments of sequences, the proposed method does not require multiple alignment and conceptually and computationally it is rather simple. ? Springer International Publishing Switzerland 2015.

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