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论文类型：期刊论文

发表时间：2018-01-01

发表刊物：SYNTHESIS-STUTTGART

收录刊物：SCIE、EI、Scopus

卷号：50

期号：2

页面范围：341-348

ISSN号：0039-7881

关键字：omega-substituted biuret; N-monosubstituted urea; potassium cyanate; dicyanic acid; selective reactions

摘要：A novel, simple, and highly efficient method has been designed for the synthesis of -substituted arylbiurets in a one-pot reaction. The primary features of this protocol include readily available starting materials, an easy work-up procedure, and yields of 51 to 87%. omega-Substituted arylbiurets can be selectively prepared with an excess of potassium cyanate (KOCN). However, use of an excess of glacial acetic acid (AcOH) switches the reaction towards the formation of N-monosubstituted urea.