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个人信息Personal Information
副教授
博士生导师
硕士生导师
性别：男
毕业院校：香港中文大学
学位：博士
所在单位：化工学院
学科：有机化学
办公地点：大连理工大学西校区，E-308
电子邮箱：liujh@dlut.edu.cn
Palladium-catalyzed geometrically selective hydrogenation of (Z)-trifluoromethyl alkenyl triflate: an efficient approach to (Z) or (E)-3,3,3-trifluoropropenyl derivatives
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论文类型：期刊论文
发表时间：2017-07-21
发表刊物：ORGANIC & BIOMOLECULAR CHEMISTRY
收录刊物：SCIE、EI、PubMed
卷号：15
期号：27
页面范围：5693-5700
ISSN号：1477-0520
摘要：A Pd-catalyzed hydrogenation of (Z)-trifluoromethyl alkenyl triflate providing either (Z) -or (E)-3,3,3-trifluoropropenyl derivatives with excellent divergent geometric control in good yield is described. Catalyzed by Pd(OAc)(2)/PPh3, the reduction of (Z)-trifluoromethyl alkenyl triflates with HSiEt3 gave (E)-3,3,3-trifluoropropenyl derivatives, and while using HCOOH/Et3N as the reducing agent, the (Z)-isomers were obtained through an elimination/hydrogenation tandem pathway. Both transformations showed excellent geometrical selectivity.