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个人信息Personal Information
副教授
博士生导师
硕士生导师
性别：男
毕业院校：香港中文大学
学位：博士
所在单位：化工学院
学科：有机化学
办公地点：大连理工大学西校区，E-308
电子邮箱：liujh@dlut.edu.cn
扫描关注
Synthesis of imidazo[1, 2-a]pyridines via the silver acetate-catalyzed Groebke-Blackburn-Bienayme reaction with ethylene glycol as a biodegradable and sustainable solvent
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论文类型：期刊论文
发表时间：2020-03-01
发表刊物：JOURNAL OF HETEROCYCLIC CHEMISTRY
收录刊物：SCIE
卷号：57
期号：3
页面范围：955-964
ISSN号：0022-152X
摘要：An efficient, silver-based catalytic system has been designed for the synthesis of biologically important 3-aminoimidazo-fused heterocycles via the Groebke-Blackburn-Bienayme reaction, in which AgOAc was used as a catalyst and ethylene glycol as a solvent from isocyanides, various aryl aldehydes and an 2-amino heterocycle were also used. Good to excellent yields, high atomic economy and environmentally friendly conditions are the potential features of this one-pot process.