Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-11-15

Journal: BIOCHEMICAL ENGINEERING JOURNAL

Included Journals: Scopus、EI、SCIE

Volume: 80

Page Number: 68-75

ISSN: 1369-703X

Key Words: 1,3-Propanediol; Fermentation; Aqueous two-phase extraction; Capture and sequestration of CO2

Abstract: An integrated fermentation-separation process for the production of 1,3-propanediol (1,3-PD) was investigated. Aqueous two-phase system (ATPS) not only recovered 97.9% of 1,3-PD, but simultaneously also removed 99.1% cells, 81.9% proteins, 75.5% organic acids, and 78.7% water. Furthermore, after extraction the bottom phase of ATPS was used to adjust the pH of the culture during fermentation, leading to 16% and 126% increases in the concentrations of 1,3-PD and lactic acid, and dramatic decreases in the concentration of acetic acid and formic acid. The total mass conversion yield of three main products (1,3-PD, 2,3-butanediol, and lactic acid) from glycerol reached 81.6%. The salt-enriched phase could also be used to absorb carbon dioxide (CO2), resulting in 94% recovery for carbonate. Finally, process simulation using the program PRO/II showed the use of ATPS reduced 75.1% of the energy expenditure and 89.0% of CO2 emissions. Crown Copyright (C) 2013 Published by Elsevier B.V. All rights reserved.