Release Time:2019-03-12  Hits:

Indexed by: Journal Article

Date of Publication: 2018-07-21

Journal: CHEMICAL COMMUNICATIONS

Included Journals: SCIE

Volume: 54

Issue: 57

Page Number: 7928-7931

ISSN: 1359-7345

Abstract: Novel and practical acid-catalyzed cyclization of 2-indolyl aryl carbinols via tandem dehydration/1,5-hydride shift/7-cyclization sequences has been developed. By appropriate variation of the substrate, diverse polycyclic-fused indoles were synthesized in good yield, thus demonstrating the high efficiency, transition-metal-free nature, and high step/atom economy of the synthesis strategy.