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Synthesis of gem-Difluoroallylboronates via FeCl2-Catalyzed Boration/beta-Fluorine Elimination of Trifluoromethyl Alkenes

Release Time:2019-03-12  Hits:

Indexed by: Journal Article

Date of Publication: 2017-02-17

Journal: ORGANIC LETTERS

Included Journals: PubMed、SCIE

Volume: 19

Issue: 4

Page Number: 946-949

ISSN: 1523-7060

Abstract: The first ferrous chloride catalyzed boration/beta-fluorine elimination of trifluoromethyl alkenes is described. Thus, a full range of gem-difluoroallylboronates were obtained in high yield under mild conditions. As an important fluorinated building block, gem-difluoroallylboronate can be readily converted into diverse difluoro-substituted species.

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