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Indexed by:期刊论文

Date of Publication:2013-06-21

Journal:ORGANIC LETTERS

Included Journals:SCIE、PubMed、Scopus

Volume:15

Issue:12

Page Number:3106-3109

ISSN No.:1523-7060

Abstract:A novel library of chiral guanidines featuring a tartaric acid skeleton was developed from diethyl L-tartrate. These guanidines are easily accessed with tunable style and electronic properties. The utilities of the guanidines were highlighted by their ability to catalyze the alpha-hydroxylation of beta-ketoesters and beta-diketones with remarkable efficiency and excellent enantioselectivity.