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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东京大学
学位：博士
所在单位：化工学院
电子邮箱：qujp@dlut.edu.cn
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Expedient Synthesis of 1,4-Benzodiazepines via a Tandem Condensation/[1,5]-Hydride Transfer/Cyclization Process
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论文类型：期刊论文
发表时间：2018-11-05
发表刊物：ADVANCED SYNTHESIS & CATALYSIS
收录刊物：SCIE、Scopus
卷号：360
期号：21
页面范围：4094-4098
ISSN号：1615-4150
关键字：[1,5]-hydride shift/cyclization; benzodiazepine; tandem reaction; C(sp(3))-H functionalization; N-heterocycle
摘要：An expedient approach to 1,4-benzodiazepines via a tandem condensation/[1,5]-hydride shift/cyclization process has been developed. This transformation started from readily available o-amino benzaldehyde and aminomalonate and was promoted by low-cost FeCl3 with high step and atom economy.