|
个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东京大学
学位：博士
所在单位：化工学院
电子邮箱：qujp@dlut.edu.cn
扫描关注
Highly Efficient and Practical Thiocyanation of Imidazopyridines Using an N-Chlorosuccinimide/NaSCN Combination
点击次数：
论文类型：期刊论文
发表时间：2016-07-01
发表刊物：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
收录刊物：SCIE
期号：20
页面范围：3373-3379
ISSN号：1434-193X
关键字：Synthetic methods; Aromatic substitution; Nitrogen heterocycles; Thiocyanates; Sulfur
摘要：A direct C-H thiocyanation of imidazo[1,2-a]pyridines, and a practical sequential one-pot condensation/C-H thiocyanation process, using a combination of N-chlorosuccinimide/NaSCN for the synthesis of 3-thiocyanatoimidazo[1,2-a]pyridines have been developed. The reactions are environmentally friendly, and easy to carry out. They use readily available starting materials and mild reaction conditions, show a wide functional group tolerance, and give good to excellent yields.