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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东京大学
学位：博士
所在单位：化工学院
电子邮箱：qujp@dlut.edu.cn
扫描关注
Asymmetric chlorination of 4-substituted pyrazolones catalyzed by natural cinchona alkaloid
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论文类型：期刊论文
发表时间：2016-09-15
发表刊物：CHEMICAL COMMUNICATIONS
收录刊物：SCIE、PubMed、Scopus
卷号：52
期号：76
页面范围：11426-11429
ISSN号：1359-7345
摘要：A natural quinidine-catalyzed asymmetric chlorination of 4-substituted pyrazolones is developed, affording products with a quaternary chiral chlorine-attached carbon centre in high yield with excellent enantio-selectivity. The low catalyst loading (1 mol%), broad substrate scope, and facile and valuable transformation of the product highlight the practical utility of this process.