Zinc chloride catalyzed stereoselective construction of spiropyrazolone tetrahydroquinolines via tandem [1,5]-hydride shift/cyclization sequence
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论文类型：期刊论文
发表时间：2015-01-01
发表刊物：RSC ADVANCES
收录刊物：Scopus、EI、SCIE
卷号：5
期号：105
页面范围：86056-86060
ISSN号：2046-2069
摘要：A zinc chloride catalyzed tandem 1,5-hydride shift/cyclization process to form spiropyrazolone terahydroquinoline derivatives is developed. A series of new spiropyrazolone derivatives were obtained in good to high yields with good to excellent diastereoselectivities (up to 95% yield, >95 : 5 dr). Additionally, the spiropyrazolone derivatives could be converted into the corresponding novel spriopyrazolines.