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论文类型：期刊论文

发表时间：2014-01-01

发表刊物：AUSTRALIAN JOURNAL OF CHEMISTRY

收录刊物：SCIE、EI、Scopus

卷号：67

期号：7

页面范围：1115-1118

ISSN号：0004-9425

摘要：A novel library of chiral guanidines featuring the tartaric acid skeleton is easily accessed with tunable steric and electronic properties. A guanidine molecule of this library with an incorporated 2,6-diisoaniline fragment was identified as a suitable promoter for the enantioselective fluorination of 1,3-dicarbonyl and alpha-cyano carbonyl compounds to furnish the fluorinated product with up to 84% ee and 99% yield using N-fluorobenzenesulfonimide (NFSI) as the fluorinating agent.