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论文类型：期刊论文

发表时间：2012-06-01

发表刊物：ORGANIC LETTERS

收录刊物：Scopus、PubMed、SCIE

卷号：14

期号：11

页面范围：2734-2737

ISSN号：1523-7060

摘要：The first highly enantio- and diastereoselective vinylogous aldol reaction between propionyl acetate-derived Brassard's diene and aldehydes was accomplished by titanium lithium combined Lewis acid, affording delta-hydroxy-gamma-methyl-beta-methoxy acrylates. This methodology was utilized in convenient and concise construction of the polypropionate moiety in cystothiazole A and mellthiazole C.