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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东京大学
学位：博士
所在单位：化工学院
电子邮箱：qujp@dlut.edu.cn
扫描关注
Highly Enantio- and Diastereoselective Vinylogous Aldol Reaction by LiCl-Assisted BINOL-Titanium Species
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论文类型：期刊论文
发表时间：2012-06-01
发表刊物：ORGANIC LETTERS
收录刊物：SCIE、PubMed、Scopus
卷号：14
期号：11
页面范围：2734-2737
ISSN号：1523-7060
摘要：The first highly enantio- and diastereoselective vinylogous aldol reaction between propionyl acetate-derived Brassard's diene and aldehydes was accomplished by titanium lithium combined Lewis acid, affording delta-hydroxy-gamma-methyl-beta-methoxy acrylates. This methodology was utilized in convenient and concise construction of the polypropionate moiety in cystothiazole A and mellthiazole C.