Intermolecular Amidation of Quinoline N-Oxides with Arylsulfonamides under Metal-Free Conditions
Release Time:2019-03-11 Hits:
Indexed by: Journal Article
Date of Publication: 2017-11-17
Journal: ORGANIC LETTERS
Included Journals: PubMed、SCIE
Volume: 19
Issue: 22
Page Number: 6088-6091
ISSN: 1523-7060
Abstract: An efficient method for the synthesis of N-(quinolin-2-yl)sulfonamides is described. The intermolecular amidation of quinoline N-oxides with sulfonamides proceeded smoothly in the presence of PhI(OAc)(2) and PPh3 to afford N-(quinolin-2-yl)sulfonamides in satisfactory to excellent yields.
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