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Intermolecular Amidation of Quinoline N-Oxides with Arylsulfonamides under Metal-Free Conditions

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Indexed by:期刊论文

Date of Publication:2017-11-17

Journal:ORGANIC LETTERS

Included Journals:SCIE、PubMed

Volume:19

Issue:22

Page Number:6088-6091

ISSN No.:1523-7060

Abstract:An efficient method for the synthesis of N-(quinolin-2-yl)sulfonamides is described. The intermolecular amidation of quinoline N-oxides with sulfonamides proceeded smoothly in the presence of PhI(OAc)(2) and PPh3 to afford N-(quinolin-2-yl)sulfonamides in satisfactory to excellent yields.

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