Palladium-catalyzed bisfunctionalization of active alkenes by beta-acetonitrile-alpha-allyl addition: application to the synthesis of unsymmetric 1,4-di(organo)fullerene derivatives
Release Time:2019-03-09 Hits:
Indexed by: Journal Article
Date of Publication: 2012-03-07
Journal: TETRAHEDRON LETTERS
Included Journals: Scopus、SCIE
Volume: 53
Issue: 10
Page Number: 1210-1213
ISSN: 0040-4039
Key Words: beta-Acetonitrile-alpha-allyl addition; Bisfunctionalization of active alkenes; All-carbon quarternary center; Unsymmetric 1,4-disubstituted C-60
Abstract: A new, efficient palladium-catalyzed bisfunctionalization of ethylidene malononitriles by addition of acetonitrile and allyl groups is developed for the construction of all-carbon quarternary and tertiary centers simultaneously. This methodology is successfully applied to the synthesis of unsymmetric 1,4-disubstituted C-60. (C) 2011 Elsevier Ltd. All rights reserved.