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Nucleophilic Dearomatization of Chloromethyl Naphthalene Derivatives via eta(3)-Benzylpalladium Intermediates: A New Strategy for Catalytic Dearomatization

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2011-10-07

Journal: ORGANIC LETTERS

Included Journals: SCIE、Scopus、PubMed

Volume: 13

Issue: 19

Page Number: 5402-5405

ISSN: 1523-7060

Abstract: Palladium-catalyzed nucleophilic dearomatization of chloromethyl naphthalene derivatives to produce ortho- or pare-substituted carbocycles in satisfactory to excellent yields has been developed. The unprecedented dearomatization reactions proceeded smoothly under mild conditions via eta(3)-benzylpalladium Intermediates.

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