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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东北大学
学位：博士
所在单位：化工学院盘锦分院
办公地点：精细化工国家重点实验室E504
电子邮箱：mingbao@dlut.edu.cn
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1-Naphthol Synthesis through Base-Promoted SNAr Reactions of ortho-Haloacetophenones Followed by Lewis-Acid-Catalyzed Cyclization
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论文类型：期刊论文
发表时间：2016-05-01
发表刊物：ASIAN JOURNAL OF ORGANIC CHEMISTRY
收录刊物：SCIE
卷号：5
期号：5
页面范围：699-704
ISSN号：2193-5807
关键字：1-naphthols; aryl halides; copper catalysis; ortho-haloacetophenones; SNAr reactions
摘要：An efficient method was developed for the synthesis of 1-naphthols through NaOtBu-promoted SNAr reaction of ortho-haloacetophenones followed by Lewis acid CuI-catalyzed intramolecular condensation and isomerization. 1-Naphthol derivatives were obtained in satisfactory yields from aryl bromide and aryl iodide substrates.