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个人信息Personal Information

教授

博士生导师

硕士生导师

性别:男

毕业院校:日本东北大学

学位:博士

所在单位:化工学院盘锦分院

办公地点:精细化工国家重点实验室E504

电子邮箱:mingbao@dlut.edu.cn

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Synthesis of 3,5-Disubstituted Pyrazoles via Cope-Type Hydroamination of 1,3-Dialkynes

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论文类型:期刊论文

发表时间:2013-02-15

发表刊物:JOURNAL OF ORGANIC CHEMISTRY

收录刊物:SCIE、EI、PubMed、Scopus

卷号:78

期号:4

页面范围:1693-1698

ISSN号:0022-3263

摘要:An efficient method for the synthesis of 3,5-disubstituted pyrazoles is described. The reactions of 1,3-dialkynes with hydrazine proceeded smoothly in dimethyl sulfoxide under mild reaction conditions to produce 3,5-disubstituted pyrazoles in satisfactory to excellent yields. A one-pot procedure of the transformation has been developed.