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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东北大学
学位：博士
所在单位：化工学院盘锦分院
办公地点：精细化工国家重点实验室E504
电子邮箱：mingbao@dlut.edu.cn
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Efficient palladium-catalyzed cyanation of aryl/heteroaryl bromides with K-4[Fe(CN)(6)] in t-BuOH-H2O using tris(2-morpholinophenyl)phosphine as a ligand
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论文类型：期刊论文
发表时间：2013-11-21
发表刊物：RSC ADVANCES
收录刊物：SCIE、EI、Scopus
卷号：3
期号：43
页面范围：20379-20384
ISSN号：2046-2069
摘要：A practical method for the synthesis of various aryl/heteroaryl nitriles using non-toxic K-4[Fe(CN)(6)] as the cyanide source is described. The cyanation of aryl/heteroaryl bromides with K-4[ Fe(CN)(6)] proceeded smoothly in the presence of a Pd/tris(2-morpholinophenyl)phosphine (L5) catalyst under mild conditions. The corresponding aryl/heteroaryl nitriles were produced in good to excellent yields.