论文成果
Copper-catalyzed aldol-type addition of ketones to aromatic nitriles: a simple approach to enaminone synthesis
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- 论文类型:期刊论文
- 发表时间:2013-04-11
- 发表刊物:CHEMICAL COMMUNICATIONS
- 收录刊物:SCIE、PubMed、Scopus
- 文献类型:J
- 卷号:49
- 期号:28
- 页面范围:2885-2887
- ISSN号:1359-7345
- 摘要:An efficient method for the synthesis of enaminones is described. The aldol-type addition of ketones to aromatic nitriles proceeded smoothly in the presence of a simple copper catalyst system (CuI-2,2'-bipyridine-(NaOBu)-Bu-t) in N,N-dimethylformamide. Enaminones in satisfactory to excellent yields were produced using this technique.