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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：日本东北大学
学位：博士
所在单位：化工学院盘锦分院
办公地点：精细化工国家重点实验室E504
电子邮箱：mingbao@dlut.edu.cn
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Propargylamine Synthesis by Copper-Catalyzed Oxidative Coupling of Alkynes and Tertiary Amine N-Oxides
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论文类型：期刊论文
发表时间：2011-08-19
发表刊物：JOURNAL OF ORGANIC CHEMISTRY
收录刊物：SCIE、EI、PubMed
卷号：76
期号：16
页面范围：6901-6905
ISSN号：0022-3263
摘要：An efficient method for synthesizing N,N-di-methylpropargylamines is described. The synthesis exploited the Cu(II)-catalyzed oxidative alkynylation reaction of tri-methylamine N-oxides with alkynes in the absence of external oxidant. Both aromatic and aliphatic allcynes were utilized to achieve the corresponding products in moderate to excellent yields. The reaction conditions tolerated ester, hydroxy, and aldehyde groups.