Hits:

Indexed by:期刊论文

Date of Publication:2014-07-04

Journal:JOURNAL OF ORGANIC CHEMISTRY

Included Journals:PubMed、SCIE、EI、Scopus

Volume:79

Issue:13

Page Number:6310-6314

ISSN No.:0022-3263

Abstract:Cyclization reactions of 2-aminophenols with beta-diketones catalyzed by a combination of Bronsted acid and CuI are presented. Various 2-substituted benzoxazoles were obtained through these reactions. Different substituents such as methyl, chloro, bromo, nitro, and methoxy on 2-aminophenol are tolerated under the optimized reaction conditions.