Current position: Home >> Scientific Research >> Paper Publications

Copper-catalyzed aldol-type addition of ketones to aromatic nitriles: a simple approach to enaminone synthesis

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-04-11

Journal: CHEMICAL COMMUNICATIONS

Included Journals: Scopus、PubMed、SCIE

Volume: 49

Issue: 28

Page Number: 2885-2887

ISSN: 1359-7345

Abstract: An efficient method for the synthesis of enaminones is described. The aldol-type addition of ketones to aromatic nitriles proceeded smoothly in the presence of a simple copper catalyst system (CuI-2,2'-bipyridine-(NaOBu)-Bu-t) in N,N-dimethylformamide. Enaminones in satisfactory to excellent yields were produced using this technique.

Prev One:新型P,N-配体的合成及其在有机合成中的应用

Next One:铜催化胺与1,3-二羰基化合物的缩合反应合成烯胺酮化合物