冯秀娟

个人信息Personal Information

教授

博士生导师

硕士生导师

性别:女

毕业院校:大连理工大学

学位:博士

所在单位:化工学院

办公地点:西部校区实验楼E506

联系方式:0411-84986181

电子邮箱:fengxiujuan@dlut.edu.cn

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Synthesis of 1,3,5-Trisubstituted Pyrazoles by the Cope-Type Hydroamination of 1,3-Dialkynes with Alkylhydrazines

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论文类型:期刊论文

发表时间:2014-09-01

发表刊物:SYNTHESIS-STUTTGART

收录刊物:SCIE、EI、Scopus

卷号:46

期号:18

页面范围:2422-2429

ISSN号:0039-7881

关键字:1,3,5-trisubstituted pyrazole; 1,3-dialkyne; alkylhydrazine; synthesis; Cope-type hydroamination

摘要:An efficient method to synthesize 1,3,5-trisubstituted pyrazoles was developed. The reaction of 1,3-dialkynes with alkylhydrazines smoothly proceeded in dimethyl sulfoxide under suitable heating conditions to produce 1,3,5-trisubstituted pyrazoles in satisfactory to excellent yields.