论文成果
Regioselective control by a catalyst switch in palladium-catalyzed benzylallylation of arylethylidene malononitriles
- 点击次数：
- 论文类型：期刊论文
- 发表时间：2013-11-15
- 发表刊物：JOURNAL OF ORGANOMETALLIC CHEMISTRY
- 收录刊物：SCIE、EI、Scopus
- 文献类型：J
- 卷号：745
- 页面范围：177-185
- ISSN号：0022-328X
- 关键字：Regioselective control; Catalyst switch; 2-(Bromomethylnaphthalene;
Arylethylidene malononitrile; Allyltributylstannane
- 摘要：Regioselective control by a catalyst switch in palladium-catalyzed benzylallylation of arylethylidene malononitriles (alpha-benzyl-beta-allylation versus alpha-allyl-beta-benzylation) is described. The three-component reaction of 2-(bromomethyl)naphthalenes, arylethylidene malononitriles, and allyltributylstannane proceeds smoothly with palladium nanoparticles as a catalyst to provide a-benzyl-b-allylation products in good yields. The regioselectivity of the benzylallylation reaction is completely overturned with Pd(PPh3)(4) as the catalyst instead of palladium nanoparticles to obtain alpha-allyl-beta-benzylation products in moderate to good yields. (C) 2013 Elsevier B.V. All rights reserved.
