Release Time:2019-03-11  Hits:

Indexed by: Journal Article

Date of Publication: 2018-04-15

Journal: SENSORS AND ACTUATORS B-CHEMICAL

Included Journals: EI、SCIE

Volume: 259

Page Number: 626-632

ISSN: 0925-4005

Key Words: Sensor; Cell; Fluorescence; Electron transfer; Free energy

Abstract: Fluorescent chemosensors are widely used in chemical engineering, bio-engineering, medical engineering, and environmental engineering. A lot of the chemosensors are based on photo-induced electron transfer (PET) process. In complicated practical systems, the proton is always the most serious interference factor. Herein a new method is proposed for PET chemosensor design to overcome the proton interference: to tune the Delta G of the electron transfer process by introducing different substituents of the sensor molecules. Chemosensors for Zn2+ detection are demonstrated. When the highest occupied molecular orbital (HOMO) energy levels of the fluorophores (4-substituted 1, 8-naphthalimide) are lower than the HOMO energy level of protonated receptor (dipicolylamine-H+), the fluorescence responding to Zn2+ ions is not influenced by pH, meanwhile, the chemosensors can work in acidic media with pH below the pKa values. This should reveal a new criterion for designing of PET based chemosensors for selectivity improvement. (C) 2017 Elsevier B.V. All rights reserved.