Release Time:2019-03-11  Hits:

Indexed by: Journal Article

Date of Publication: 2018-06-15

Journal: SENSORS AND ACTUATORS B-CHEMICAL

Included Journals: EI、SCIE

Volume: 263

Page Number: 661-667

ISSN: 0925-4005

Key Words: Artificial fluorescent protein; Fluorescent recognition; Relay sensing; Silver ion; Nanosensor

Abstract: Green fluorescent protein (GFP) becomes one of the most important imaging tools in biology and biomedicine. To simplify usage, expand the application and avoid complicated operations, a kind of artificial fluorescent protein (AFP) is inspired and fabricated by lighting up human serum albumin (HSA) with loading microenvironment-sensitive fluorescent dye DMAR, which could be applied in HSA assay in human urine and serum samples as a physiological indicator of diagnosis in clinical. Besides, the AFP, DMAR/HSA, could act as a nanosensor for Ag+ sensing with good selectivity by a new relay recognition strategy. (C) 2018 Elsevier B.V. All rights reserved.