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染料分子激发态释能调控与功能强化

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Indexed by:会议论文

Date of Publication:2012-04-13

Page Number:1-1

Key Words:染料;分子探针;成像;内转换;荧光

Abstract:  通过设计不对称菁类染料的关键基团转动,使染料在自由态几乎成为暗态,但与DNA沟槽结合后,转动抑制而发射荧光,从而得到对活细胞核仁DNA具有专一性响应的用廉价半导体激光器可激发的近红外荧光染料(DEAB-TO-3),蛋白质和RNA干扰低、灵敏高,可实现对活细胞核仁进行DNA进行定量及成像,已用于五分类血液细胞分析系统。

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