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Indexed by:期刊论文

Date of Publication:2013-01-14

Journal:TETRAHEDRON

Included Journals:SCIE、Scopus

Volume:69

Issue:2

Page Number:636-641

ISSN No.:0040-4020

Key Words:Nitric oxide; Rhodamine; Cu2+; Fluorescence imaging

Abstract:Two rhodamine-based NO probes were designed and synthesized. Both RB-TP and RB-Py can detect NO by spectroscopic and 'naked-eye' methods in HEPES buffer assisted by Cu2+. The detection limits for NO were 5 nM and 20 nM, respectively. Other biologically relevant reactive species, such as NO2-, NO3-, OONO-, H2O2, O-1(2), and ClO- did not give any obvious interferences. RB-TP and RB-Py have been also applied to detect the intracellular NO by fluorescence imaging method. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.