Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-01-14

Journal: TETRAHEDRON

Included Journals: Scopus、SCIE

Volume: 69

Issue: 2

Page Number: 636-641

ISSN: 0040-4020

Key Words: Nitric oxide; Rhodamine; Cu2+; Fluorescence imaging

Abstract: Two rhodamine-based NO probes were designed and synthesized. Both RB-TP and RB-Py can detect NO by spectroscopic and 'naked-eye' methods in HEPES buffer assisted by Cu2+. The detection limits for NO were 5 nM and 20 nM, respectively. Other biologically relevant reactive species, such as NO2-, NO3-, OONO-, H2O2, O-1(2), and ClO- did not give any obvious interferences. RB-TP and RB-Py have been also applied to detect the intracellular NO by fluorescence imaging method. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.