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A FRET approach for luminescence sensing Cr3+ in aqueous solution and living cells through functionalizing glutathione and glucose moieties

Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2011-02-11

Journal: TETRAHEDRON

Included Journals: SCIE、Scopus

Volume: 67

Issue: 6

Page Number: 1091-1095

ISSN: 0040-4020

Key Words: Chemosensor; Cr3+; Glucose tolerance factors; FRET

Abstract: A simple FRET-based approach to ratiometric fluorescence sensing of Cr3+ in aqueous solution using glutathione and glucose as building blocks was achieved, inspired to the binding motifs of Cr3+ in glucose tolerance factors (GTF). Selectivity and competition experiments showed that this system featured high sensitivity (detection limit <= 0.1 ppm) and excellent selectivity over other metal ions in buffer solution. Confocal fluorescence microscopy experiments had established the utility of the approach in monitoring Cr3+ within living cells. (C) 2010 Elsevier Ltd. All rights reserved.

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