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教授

博士生导师

硕士生导师

性别:男

毕业院校:南京大学

学位:博士

所在单位:化工学院

电子邮箱:hecheng@dlut.edu.cn

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A cerium-based metal-organic tetrahedron for fluorescent recognition of 5-HIAA and its application in urine test

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论文类型:期刊论文

发表时间:2016-11-01

发表刊物:INORGANIC CHEMISTRY COMMUNICATIONS

收录刊物:SCIE、Scopus

卷号:73

页面范围:129-133

ISSN号:1387-7003

关键字:Urine test; Tumor marker; Fluorescent sensor

摘要:A cerium-based metal-organic tetrahedron including triphenylamine was applied to recognize the 5-hydroxyindole-3-acetic acid (5-HIAA), a kind of tumor marker and playing crucial roles in the process of the disease diagnosis and clinical treatment. The tetrahedron could encapsulate 5-HIAA through weak interaction and space stereoselectivity, and it displayed good fluorescence enhancement towards 5-HIAA over other relevant species in urine. The tetrahedral sensor is capable of detecting 5-HIAA with good selectivity and high sensitivity in real urine. (C) 2016 Elsevier B.V. All rights reserved.