点击次数：

论文类型：期刊论文

发表时间：2011-02-11

发表刊物：CARBOHYDRATE POLYMERS

收录刊物：SCIE、EI

卷号：84

期号：1

页面范围：465-470

ISSN号：0144-8617

关键字：Chitosan derivative; Poly(vinyl alcohol); Crosslinking; Swelling; Antibacterial

摘要：Novel crosslinked blend films of N-(2-hydroxy)propyl-3-trimethylammonium chitosan chloride (HTCC) and poly(vinyl alcohol) (PVA) were prepared by mixing their aqueous solutions followed by crosslinking with glutaraldehyde (GA). The effects of the GA content and ratio of HTCC to PVA on the appearance, swelling, gel content, morphology and antibacterial activities of blend films were studied and a possible mechanism of crosslinking was proposed based on the results. It was found that the equilibrium degree of swelling (ESD) increased with the increasing content of HTCC, but decreased with the content of GA. The ESD was a maximum (212%) when the ratio of HTCC/PVA/GA was 60/40/2 (wt). Antibacterial activities against Staphylococcus aureus and Escherichia coli of the blend films were weakened slightly by crosslinking, but still showed substantial antibacterial activity. These results demonstrate that, not only the PVA, but also the HTCC reacted with GA. It was the amino groups on HTCC that was un-substituted by quaternary ammonium salt, which reacted with the aldehyde groups on GA. (C) 2010 Elsevier Ltd. All rights reserved.