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Indexed by:期刊论文

Date of Publication:2014-03-17

Journal:SYNLETT

Included Journals:SCIE、Scopus

Volume:25

Issue:5

Page Number:724-728

ISSN No.:0936-5214

Key Words:reductions; aldol reactions; lactones; domino reactions; copper; catalysis

Abstract:The first copper-catalyzed reductive aldol addition/lactonization domino reactions of alpha,beta-unsaturated dicarboxylate esters with ketones were achieved in high yields. The method, which involves easily available reagents, a flexible combination of reactants, and mild conditions, provides a simple route to functionalized lactones bearing an ester group.