Indexed by:期刊论文
Date of Publication:2012-02-15
Journal:BIOSENSORS & BIOELECTRONICS
Included Journals:SCIE、EI、PubMed
Volume:32
Issue:1
Page Number:293-296
ISSN No.:0956-5663
Key Words:Graphene nanoribbon; High selectivity; Cysteine; Electrochemical method
Abstract:Selective detection of cysteine in serum samples was achieved on a graphene nanoribbon (GNR) and Nafion nanocomposite modified electrode with high precision. The superior conductivity and abundant amount of active chemical oxygen groups on the edge of GNR led to extremely highly electrocatalytic activity of GNR towards the electrochemical oxidation of cysteine at +0.025 V. The electrocatalytic behavior was further used for sensitive detection of cysteine by differential pulse voltammetry. Under optimized conditions, the calibration curve was linear in the range from 25 nM to 500 mu M. The electrochemical sensor showed strong antifouling ability, good stability and selectivity. It could effectively exclude the interferences from other kinds of biothiols and the biological relevant species, thus had great perspective for in vivo analysis of biological samples. (C) 2011 Elsevier B.V. All rights reserved.
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Professor
Supervisor of Doctorate Candidates
Supervisor of Master's Candidates
Main positions:化学学院副院长
Other Post:辽宁省教学名师,宝钢优秀教师特等奖提名奖,中国分析测试学会青年学术委员会委员
Gender:Female
Alma Mater:南京大学
Degree:Doctoral Degree
School/Department:化学学院
Discipline:Analytical Chemistry. Biochemistry and Molecular Biolog
Business Address:化工综合楼C305
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