吴硕

个人信息Personal Information

教授

博士生导师

硕士生导师

主要任职:化学学院副院长

其他任职:辽宁省教学名师,宝钢优秀教师特等奖提名奖,中国分析测试学会青年学术委员会委员

性别:女

毕业院校:南京大学

学位:博士

所在单位:化学学院

学科:分析化学. 生物化学与分子生物学

办公地点:化工综合楼C305

电子邮箱:wushuo@dlut.edu.cn

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Selective electrochemical detection of cysteine in complex serum by graphene nanoribbon

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论文类型:期刊论文

发表时间:2012-02-15

发表刊物:BIOSENSORS & BIOELECTRONICS

收录刊物:SCIE、EI、PubMed

卷号:32

期号:1

页面范围:293-296

ISSN号:0956-5663

关键字:Graphene nanoribbon; High selectivity; Cysteine; Electrochemical method

摘要:Selective detection of cysteine in serum samples was achieved on a graphene nanoribbon (GNR) and Nafion nanocomposite modified electrode with high precision. The superior conductivity and abundant amount of active chemical oxygen groups on the edge of GNR led to extremely highly electrocatalytic activity of GNR towards the electrochemical oxidation of cysteine at +0.025 V. The electrocatalytic behavior was further used for sensitive detection of cysteine by differential pulse voltammetry. Under optimized conditions, the calibration curve was linear in the range from 25 nM to 500 mu M. The electrochemical sensor showed strong antifouling ability, good stability and selectivity. It could effectively exclude the interferences from other kinds of biothiols and the biological relevant species, thus had great perspective for in vivo analysis of biological samples. (C) 2011 Elsevier B.V. All rights reserved.