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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：兰州大学
学位：博士
所在单位：化工学院
学科：有机化学. 药物化学. 精细化工
办公地点：西部校区化工实验楼G-413
联系方式：0411-84986190 15942819406
电子邮箱：bmwang@dlut.edu.cn
1,3-Dipolar Cycloaddition of Azomethine Ylides Involving 3-Aminooxindoles: Versatile Construction of Dispiro[pyrrolidine-2,3 '-oxindole] Scaffolds
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论文类型：期刊论文
发表时间：2016-11-01
发表刊物：EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
收录刊物：SCIE
期号：32
页面范围：5335-5339
ISSN号：1434-193X
关键字：Cycloaddition; Diastereoselectivity; Heterocycles; Multicomponent reactions; Spiro compounds
摘要：A three-component [3+2] cycloaddition involving 3-aminooxindoles, aldehydes, and methyleneindolinone derivatives for the synthesis of dispiro[pyrrolidine-2,3'-oxindole] derivatives was developed. This reaction involves the use of readily available starting materials and mild reaction conditions. It displays broad functional-group tolerance and provides the products in high yields with good to excellent diastereoselectivities.