|
个人信息Personal Information
教授
博士生导师
硕士生导师
性别：男
毕业院校：兰州大学
学位：博士
所在单位：化工学院
学科：有机化学. 药物化学. 精细化工
办公地点：西部校区化工实验楼G-413
联系方式：0411-84986190 15942819406
电子邮箱：bmwang@dlut.edu.cn
扫描关注
Zinc chloride catalyzed stereoselective construction of spiropyrazolone tetrahydroquinolines via tandem [1,5]-hydride shift/cyclization sequence
点击次数：
论文类型：期刊论文
发表时间：2015-01-01
发表刊物：RSC ADVANCES
收录刊物：SCIE、EI、Scopus
卷号：5
期号：105
页面范围：86056-86060
ISSN号：2046-2069
摘要：A zinc chloride catalyzed tandem 1,5-hydride shift/cyclization process to form spiropyrazolone terahydroquinoline derivatives is developed. A series of new spiropyrazolone derivatives were obtained in good to high yields with good to excellent diastereoselectivities (up to 95% yield, >95 : 5 dr). Additionally, the spiropyrazolone derivatives could be converted into the corresponding novel spriopyrazolines.