Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2012-08-15

Journal: INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Included Journals: Scopus、EI、SCIE

Volume: 51

Issue: 32

Page Number: 10695-10701

ISSN: 0888-5885

Abstract: A mechanochemical pretreatment was used prior to aqueous extraction of eleutheroside B from Eleuthero coccus. senticosus. The effects of the mechanochemical assisted extraction parameters hydroxypropyl-beta-cyclodextrin (HP-beta-CD) content, particle size, and circulating water temperature on the extraction yield of eleutheroside B were investigated. The mechanochemical assisted extraction process was optimized based on an orthogonal experimental design. The optimum process conditions were a HP-beta-CD content of 23% (w/w), a particle size of D-95 <= 44 mu m and circulating water temperature of 40 degrees C. The mechanochemical assisted extraction process produced a higher eleutheroside B extraction yield, using a shorter extraction time and a greatly simplified process compared with traditional heat-reflux extraction, which makes mechanochemical assisted extraction a potential tool for eleutheroside B extraction from Eleutherococcus senticosus. Moreover, this technique used water as the solvent, making mechanochemical assisted extraction a less expensive and eco-friendly technique compared with traditional heat-reflux extraction.