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论文类型：期刊论文

发表时间：2015-08-25

发表刊物：JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY

收录刊物：SCIE、PubMed、Scopus

卷号：6

期号：1

页面范围：40

ISSN号：2049-1891

关键字：Diarrhea; Disease control; Egg yolk antibodies; IgY; Swine

摘要：In recent years, the use of in-feed antibiotics for growth and disease prevention in livestock production has been under severe scrutiny. The use and misuse of in-feed antibiotics has led to problems with drug residues in animal products and increased bacterial resistance. Chicken egg yolk antibodies (IgY) have attracted considerable attention as an alternative to antibiotics to maintain swine health and performance. Oral administration of IgY possesses many advantages over mammalian IgG such as cost-effectiveness, convenience and high yield. This review presents an overview of the potential to use IgY immunotherapy for the prevention and treatment of swine diarrhea diseases and speculates on the future of IgY technology. Included are a review of the potential applications of IgY in the control of enteric infections of either bacterial or viral origin such as enterotoxigenic Escherichia coli, Salmonella spp., rotavirus, porcine transmissible gastroenteritis virus, and porcine epidemic diarrhea virus. Some potential obstacles to the adoption of IgY technology are also discussed.