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论文类型：期刊论文

发表时间：2011-11-01

发表刊物：BIOTECHNOLOGY ADVANCES

收录刊物：Scopus、SCIE、EI、PubMed

卷号：29

期号：6

页面范围：860-868

ISSN号：0734-9750

关键字：Egg yolk immunoglobulin; IgY; Terrestrial; Aquatic; Disease control

摘要：Oral administration of chicken egg yolk immunoglobulin (IgY) has attracted considerable attention as a means of controlling infectious diseases of bacterial and viral origin. Oral administration of IgY possesses many advantages compared with mammalian IgG including cost-effectiveness, convenience and high yield. This review presents an overview of the potential to use IgY immunotherapy for the prevention and treatment of terrestrial and aquatic animal diseases and speculates on the future of IgY technology. Included are a review of the potential application of IgY for the treatment of livestock diseases such as mastitis and diarrhea, poultry diseases such as Salmonella, Campylobacteriosis, infectious bursal disease and Newcastle disease, as well as aquatic diseases like shrimp white spot syndrome virus, Yersina ruckeri and Edwardsiella tarda. Some potential obstacles to the adoption of IgY technology are also discussed. (C) 2011 Elsevier Inc. All rights reserved.