个人信息Personal Information
教授
博士生导师
硕士生导师
主要任职:计算机科学与技术学院党委书记
性别:男
毕业院校:吉林大学
学位:博士
所在单位:计算机科学与技术学院
学科:计算机应用技术
办公地点:海山楼A1022
联系方式:hwge@dlut.edu.cn
电子邮箱:gehw@dlut.edu.cn
An automatic motif recognition algorithm in DNA sequences based on particle swarm optimization and random projection
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论文类型:会议论文
发表时间:2017-01-01
收录刊物:CPCI-S
卷号:2017-January
页面范围:2241-2243
关键字:motif recognition; random projection; particle swarm optimization
摘要:Motif recognition plays a significant role for understanding the biological meanings of sequences. In this paper, a particle swarm optimization and random projection based algorithm (PSORPS) is proposed for recognizing DNA motifs. First, noise subsequences are filtered by a random projection strategy for constructing objective space. Then the PSO is used to automatically search the motifs of DNA sequences in the constructed l-mer objective space. Finally, the operators of independent drift and associated drift are conducted on the optimization results to alleviate base deviation. The experiments are carried out on real-world biological datasets, and the results validate the effectiveness of the proposed algorithm.