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论文类型：期刊论文

发表时间：2016-01-15

发表刊物：IEEE PHOTONICS TECHNOLOGY LETTERS

收录刊物：SCIE、EI、Scopus

卷号：28

期号：2

页面范围：213-216

ISSN号：1041-1135

关键字：Surface plasmon resonance; fiber-optic; biosensor; temperature compensation; Fabry-Perot interference

摘要：A temperature-compensating fiber-optic surface plasmon resonance (SPR) biosensor based on a Fabry-Perot (FP) interference is described and demonstrated in this letter. The sensing element includes an SPR measuring signal and an FP referencing signal, which appear on gold-coated multimode fiber and capillary, respectively. Because the FP sensing element is sensitive to temperature while insensitive to the refractive index, the referencing channel compensates for the impact of external ambient temperature and enhances the accuracy and reliability of the biosensor. The performance of the temperature-compensating SPR biosensor for accurate measurements is evaluated through the specific binding between Con A and RNase B under interference temperature. In addition, the design and fabrication of the temperature-compensating fiber SPR biosensor are cost effective and simple.