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论文类型：期刊论文

发表时间：2015-12-01

发表刊物：SENSORS AND ACTUATORS B-CHEMICAL

收录刊物：SCIE、EI、Scopus

卷号：220

页面范围：1217-1223

ISSN号：0925-4005

关键字：Surface plasmon resonance; Fiber-optic sensor; Boronic acid; Saccharide

摘要：To extend the application of fiber-optic surface plasmon resonance (SPR) sensing technology, the chemical molecular, 2-(((6-aminohexyl)(benzyl)amino)methyl) phenyl boronic acid (ABA-PBA), is prepared as the recognition monolayer and immobilized on the fiber-optic SPR probe. The boronic acid moiety in ABA-PBA monolayer can covalently bond with 1, 2- or 1, 3- diols moiety of sugar. A monolayer of ABA-PBA is assembled on the SPR sensing region and confirmed by surface enhanced Raman scattering (SERS) technique. Spectrophotometric method is used to determine the pKa of ABA-PBA. The interaction between ABA-PBA monolayer and saccharide can induce the shift of resonance wavelength. By using the miniature fiber-optic SPR sensor, saccharide concentration can be monitored in real time. It shows good selectivity to fructose at low concentrations (10-50 mM). (C) 2015 Elsevier B.V. All rights reserved.