Carboxylative coupling reaction of five-membered (chloromethyl) heteroarenes with allyltributylstannane catalyzed by palladium nanoparticles
Release Time:2019-03-09 Hits:
Indexed by: Journal Papers
Date of Publication: 2015-12-02
Journal: TETRAHEDRON LETTERS
Included Journals: Scopus、SCIE
Volume: 56
Issue: 48
Page Number: 6747-6750
ISSN: 0040-4039
Key Words: Palladium nanoparticles; Carbon dioxide; Carboxylative coupling
Abstract: The palladium-catalyzed three-component coupling reaction of five-membered (chloromethyl) heteroarenes, allyltributylstannane, and carbon dioxide (carboxylative Stille coupling reaction) was successfully conducted to produce beta,gamma-unsaturated esters in satisfactory to good yields. The carboxylative Stille coupling reaction occurred smoothly under mild conditions in the presence of palladium nanopartides through the formation of pi-allylpalladium chloride intermediates. (C) 2015 Elsevier Ltd. All rights reserved.