location： Current position: Home >> Scientific Research >> Paper Publications

Synthesis of 1,3,5-Trisubstituted Pyrazoles by the Cope-Type Hydroamination of 1,3-Dialkynes with Alkylhydrazines

Hits:

Indexed by:期刊论文

Date of Publication:2014-09-01

Journal:SYNTHESIS-STUTTGART

Included Journals:SCIE、EI、Scopus

Volume:46

Issue:18

Page Number:2422-2429

ISSN No.:0039-7881

Key Words:1,3,5-trisubstituted pyrazole; 1,3-dialkyne; alkylhydrazine; synthesis; Cope-type hydroamination

Abstract:An efficient method to synthesize 1,3,5-trisubstituted pyrazoles was developed. The reaction of 1,3-dialkynes with alkylhydrazines smoothly proceeded in dimethyl sulfoxide under suitable heating conditions to produce 1,3,5-trisubstituted pyrazoles in satisfactory to excellent yields.

Pre One:Chemoselective reduction of alpha,beta-unsaturated aldehydes using an unsupported nanoporous gold catalyst

Next One:Bronsted Acid Catalyzed Cyclization of 2-Amino Thiophenols/ Anilines with β-Diketones : Synthesis of Benzothiazoles and Benzimidazoles
Recommended Ph.D.Supervisor Recommended MA Supervisor Institutional Repository Personal Page

Address: No.2 Linggong Road, Ganjingzi District, Dalian City, Liaoning Province, P.R.C., 116024

Click : times
  • MOBILE Version
    •
    Open time:..
    The Last Update Time:..

    Mobile phone sweep