Release Time:2019-03-09  Hits:

Indexed by: Journal Article

Date of Publication: 2013-11-21

Journal: RSC ADVANCES

Included Journals: Scopus、EI、SCIE

Volume: 3

Issue: 43

Page Number: 20379-20384

ISSN: 2046-2069

Abstract: A practical method for the synthesis of various aryl/heteroaryl nitriles using non-toxic K-4[Fe(CN)(6)] as the cyanide source is described. The cyanation of aryl/heteroaryl bromides with K-4[ Fe(CN)(6)] proceeded smoothly in the presence of a Pd/tris(2-morpholinophenyl)phosphine (L5) catalyst under mild conditions. The corresponding aryl/heteroaryl nitriles were produced in good to excellent yields.