点击次数：

论文类型： 期刊论文

发表时间： 2011-08-19

发表刊物： JOURNAL OF ORGANIC CHEMISTRY

收录刊物： SCIE、EI、PubMed

卷号： 76

期号： 16

页面范围： 6901-6905

ISSN号： 0022-3263

摘要： An efficient method for synthesizing N,N-di-methylpropargylamines is described. The synthesis exploited the Cu(II)-catalyzed oxidative alkynylation reaction of tri-methylamine N-oxides with alkynes in the absence of external oxidant. Both aromatic and aliphatic allcynes were utilized to achieve the corresponding products in moderate to excellent yields. The reaction conditions tolerated ester, hydroxy, and aldehyde groups.