Hits:

Date of Publication:2022-10-09

Journal:现代生物医学进展

Volume:17

Issue:14

Page Number:2674-2677

ISSN No.:1673-6273

Abstract:Objective:To investigate the effects of core decompression combined with stem cell transplantation on the serum levels of PINP,CTX and OST in patients with femoral head necrosis and its clinical efficacy.Methods:76 patients with femoral head necrosis who were diagnosed and treated in our hospital were selected and randomly divided into two groups,with 38 cases in each group.The patients in the control group were treated with stem cell transplantation,while the patients in the experimental group were treated with core decompression therapy on the basis of the control group.Then the hip Harris score and the serum levels of PINP,CTX and OST of patients in the two groups were observed and compared before and after treatment.Results:The total effective rate and Harris score of experimental group were higher than those of the control group (P＜0.05).The serum levels of PINP,CTX and OST in the experimental group were obviously decreased,which were significantly lower than those of the control group (P＜0.05).Conclusion:Core decompression combined with stem cell transplantation could improve the efficacy and function of hip joint,it might be related to the reduction of serum levels of PINP,CTX and OST levels.

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